On March 6, 2018, the Missouri Supreme Court declined to review the October 17, 2017 decision by Missouri’s Eastern District Court of Appeals in Fox v. Johnson & Johnson, which had overturned the trial court’s $72-million talc verdict against the defendant. The Eastern District found that the trial court lacked personal jurisdiction over Johnson & Johnson for the claims filed by Jacqueline Fox. The decision by Missouri’s highest court, which concerned the first of five major talc verdicts entered against Johnson & Johnson, not only clears the way for Johnson & Johnson’s success in the pending appeals of three other multimillion-dollar verdicts issued by St. Louis City jurors and supports a California trial judge’s October 2017 decision to vacate a fifth $417 million verdict, but could herald a fundamental change in how mass tort cases may be litigated.